Design of Extended Release Matrix Tablet of Tramadol hydrochloride Using Combination of Hydrophobic and Hydrophilic Polymer
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چکیده
منابع مشابه
Preparation and release study of Levetiracetam 500 mg extended release tablet by using combination of hydrophilic and hydrophobic polymers.
Abstract Levetiracetam as an Anti-epileptic drug with exclusive mechanism of action is accepted by the USA Food and Drug Administration as an adjunctive therapy in treating epilepsy in young adults. The purpose of this project is the design and formulation of prolonged release of levetiracetam using two types of retarding agent such as Hydroxyl Propyl Methylcellulose (HPMC K4...
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Venlafaxine Hcl is an anti-depressant drug which is used in depression. The aim of present investigation was to prepare an ER tablet of Venlafaxine Hcl with similar dissolution profile matching to Effexor ER. An immediate release core tablet of 100mg was prepared and it was compression coated using HPMC matrix system. HPMC of three viscosity grades i.e., K4M, K15M, K100M and different concentra...
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Purpose: The objective of this study was to prepare Propranolol Hydrochloride controlled release matrix tablets and to investigate the effect of the polymer blends and the polymer concentration on drug release. Method: Propranolol Hydrochloride controlled release matrix tablets were prepared by direct compression technique. Hydroxypropylmethylcellulose K15M (HPMC K15M) and Carbopol 934P were us...
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Purpose: The objective of this study was to prepare Propranolol Hydrochloride controlled release matrix tablets and to investigate the effect of the polymer blends and the polymer concentration on drug release. Method: Propranolol Hydrochloride controlled release matrix tablets were prepared by direct compression technique. Hydroxypropylmethylcellulose K15M (HPMC K15M) and Carbopol 934P were us...
متن کاملFormulation design and in-vitro release profile evaluation of Theophylline hydrochloride sustained release tablet using different polymer at different concentration
The aim of the work was to develop Theophylline hydrochloride sustain release tablet using Methocel k 15 MCR, Methocel K100M CR premium and Methocel K4M CR premium in blending and granulation stage of processing and evaluate their physico-chemical properties and also compared the dissolution profile with the marketed drugs.Tablets were prepared by wet granulation method. The active ingredient, ...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences and Drug Research
سال: 2017
ISSN: 0975-248X
DOI: 10.25004/ijpsdr.2017.090502